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| 产品货号： | E-AB-F1192A |
|---|---|
| 英文名称： | Purified Anti-Mouse CD366/Tim-3 Antibody[RMT3-23] |
| 产品分类： | 流式纯抗 |
| 说明书（链接）： | https://789.bio/ea/au5xi9 |
| Reactivity： | Mouse |
| Isotype： | Rat IgG2a, κ |
| Clonality： | Monoclonal |
| Abbre： | CD366/Tim-3 |
| Swissprot： | Q8VIM0 | Links: https://www.uniprot.org/uniprot/Q8VIM0 |
| Concentration： | ≥ 1 mg/mL |
| Storage： | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Research Areas： | Immunology; Inhibitory Molecules |
| CloneNo： | RMT3-23 |
| Conjugation： | Unconjugated |
| Background： | CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance. |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Storage Buffer： | PBS, pH 7.2. Contains 0.05% proclin 300. |
| Expiration Date： | 12个月 |
| Shipping： | Ice bag |
| Host： | Rat |
| Alternate Names： | TIMD3, HAVcr-2, TIM3, TIMD-3 |
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