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| 产品货号： | E-AB-F1012A |
|---|---|
| 英文名称： | Purified Anti-Human CD86 Antibody[BU63] |
| 产品分类： | 流式纯抗 |
| 说明书（链接）： | https://789.bio/ea/HlWeyD |
| Reactivity： | Human |
| Isotype： | Mouse IgG1, κ |
| Verified Samples： | Verified Samples in FCM: Human peripheral blood monocyte |
| Dilution： | FCM 2 μg/mL(1×10^5-5×10^5 cells) |
| Clonality： | Monoclonal |
| Abbre： | CD86 |
| Swissprot： | P42081 | Links: https://www.uniprot.org/uniprot/P42081 |
| Concentration： | ≥ 1 mg/mL |
| Storage： | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Research Areas： | Cell Biology; Costimulatory Molecules; Immunology; Neuroscience; Neuroscience Cell Markers |
| CloneNo： | BU63 |
| Conjugation： | Unconjugated |
| Background： | CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells. |
| Leadtime： | 咨询 |
| Applications： | FCM;Block |
| Storage Buffer： | PBS, pH 7.2. Contains 0.05% proclin 300. |
| Expiration Date： | 12个月 |
| Shipping： | Ice bag |
| Host： | Mouse |
| Alternate Names： | Activation B7-2 antigen, Cd86, ETC-1, Early T-cell costimulatory molecule 1, T-lymphocyte activation antigen CD86 |
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