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| 产品货号： | E-AB-F1012B |
|---|---|
| 英文名称： | Biotin Anti-Human CD86 Antibody[BU63] |
| 产品分类： | 流式抗体 |
| 文献（数量）： | 1 |
| 说明书（链接）： | https://789.bio/ea/G8GiH0 |
| Reactivity： | Human |
| Isotype： | Mouse IgG1, κ |
| Clonality： | Monoclonal |
| Abbre： | CD86 |
| Swissprot： | P42081 | Links: https://www.uniprot.org/uniprot/P42081 |
| Cellular Localization： | Membrane |
| Concentration： | 0.5 mg/mL |
| Storage： | This product can be stored at 2-8°C for 12 months. Do not freeze. |
| CloneNo： | BU63 |
| Conjugation： | Biotin |
| Background： | CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells. |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Form： | Liquid |
| Storage Buffer： | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Expiration Date： | 12个月 |
| Shipping： | 冰袋 |
| Host： | Mouse |
| Isotype Control： | Biotin Mouse IgG1, κ Isotype Control[MOPC-21] | Links: /p-biotin_mouse_igg1_isotype_control_mopc_21-e_ab_f09793b |
| Gene ID： | 942 | Links: https://www.ncbi.nlm.nih.gov/gene/942 |
| Alternate Names： | Activation B7-2 antigen, Cd86, ETC-1, Early T-cell costimulatory molecule 1, T-lymphocyte activation antigen CD86 |
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