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| 产品货号： | E-AB-F1067A |
|---|---|
| 英文名称： | Purified Anti-Human CD57 Antibody[HNK-1] |
| 产品分类： | 流式纯抗 |
| 说明书（链接）： | https://789.bio/ea/KpqL0C |
| Reactivity： | Human |
| Isotype： | Mouse IgM, κ |
| Verified Samples： | Verified Samples in FCM: Human peripheral blood lymphocytes |
| Dilution： | FCM 2 μg/mL(1×10^5-5×10^5 cells) |
| Clonality： | Monoclonal |
| Abbre： | CD57 |
| Swissprot： | Q9P2W7 | Links: https://www.uniprot.org/uniprot/Q9P2W7 |
| Concentration： | ≥ 1 mg/mL |
| Storage： | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Research Areas： | Costimulatory Molecules, Immunology |
| CloneNo： | HNK-1 |
| Conjugation： | Unconjugated |
| Background： | CD57, also known as HNK-1, NK-1, and Leu-7 is a 100-115 kD oligosaccharide antigenic determinant expressed on a variety of proteins, lipids, and chondroitin sulfate proteoglycans. CD57 is expressed on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells, and is also expressed on neural cells and striated muscle. CD57 is not expressed on red blood cells, granulocytes, monocytes, or platelets. While the function of CD57 is unknown, binding to L-selectin, P-selectin, and a fragment of laminin suggests that CD57 may be involved in cell-matrix interactions. CD57 is increased in some disease states associated with CD4/CD8 imbalances (AIDS, autoimmune disease, viral infections, and allograft transplants). |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Storage Buffer： | PBS, pH 7.2. Contains 0.05% proclin 300. |
| Expiration Date： | 12个月 |
| Shipping： | Ice bag |
| Host： | Mouse |
| Alternate Names： | HNK-1, Leu-7, NK-1 |
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