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| 产品货号： | E-AB-F1075A |
|---|---|
| 英文名称： | Purified Anti-Human CD32 Antibody[IV-3] |
| 产品分类： | 流式纯抗 |
| 说明书（链接）： | https://789.bio/ea/SZ58OC |
| Reactivity： | Human |
| Isotype： | Mouse IgG2b, κ |
| Verified Samples： | Verified Samples in FCM: Human peripheral blood granulocyte |
| Dilution： | FCM 2 μg/mL(1×10^5-5×10^5 cells) |
| Clonality： | Monoclonal |
| Immunogen： | Recombinant Human CD32 protein |
| Abbre： | CD32 |
| Swissprot： | P31994 | Links: https://www.uniprot.org/uniprot/P31994 |
| Concentration： | ≥ 1 mg/mL |
| Storage： | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Purification Method： | >98%, Protein A/G purified |
| Research Areas： | Immunology; Innate Immunity |
| CloneNo： | IV-3 |
| Conjugation： | Unconjugated |
| Background： | CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform). |
| Leadtime： | 咨询 |
| Applications： | FCM;Block |
| Storage Buffer： | PBS, pH 7.2. Contains 0.05% proclin 300. |
| Expiration Date： | 12个月 |
| Shipping： | Ice bag |
| Host： | Mouse |
| Alternate Names： | IGFR2, CD32, CDw32, FCG2, FCGR2B, Fc-gamma RII-b, Fc-gamma-RIIb, FcRII-b, IgG Fc receptor II-b, Low affinity immunoglobulin gamma Fc region receptor II-b |
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