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| 产品货号： | E-AB-F1075B |
|---|---|
| 英文名称： | Biotin Anti-Human CD32 Antibody[IV-3] |
| 产品分类： | 流式抗体 |
| 说明书（链接）： | https://789.bio/ea/i5iDqD |
| Reactivity： | Human |
| Isotype： | Mouse IgG2b, κ |
| Clonality： | Monoclonal |
| Abbre： | CD32 |
| Swissprot： | P31994 | Links: https://www.uniprot.org/uniprot/P31994 |
| Cellular Localization： | Membrane |
| Concentration： | 0.5 mg/mL |
| Storage： | This product can be stored at 2-8°C for 12 months. Do not freeze. |
| CloneNo： | IV-3 |
| Conjugation： | Biotin |
| Background： | CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform). |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Form： | Liquid |
| Storage Buffer： | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Expiration Date： | 12个月 |
| Shipping： | 冰袋 |
| Host： | Mouse |
| Isotype Control： | Biotin Mouse IgG2b, κ Isotype Control[MPC-11] | Links: /p-biotin_mouse_igg2b_isotype_control_mpc_11-e_ab_f09813b |
| Gene ID： | 2212 | Links: https://www.ncbi.nlm.nih.gov/gene/2212 |
| Alternate Names： | IGFR2, CD32, CDw32, FCG2, FCGR2B, Fc-gamma RII-b, Fc-gamma-RIIb, FcRII-b, IgG Fc receptor II-b, Low affinity immunoglobulin gamma Fc region receptor II-b |
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