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| 产品货号： | E-AB-F1366J |
|---|---|
| 英文名称： | PerCP/Cyanine5.5 Anti-Human CD194/CCR4 Antibody[L291H4] |
| 产品分类： | 流式抗体 |
| 说明书（链接）： | https://789.bio/ea/1OOSSS |
| Reactivity： | Human |
| Isotype： | Mouse IgG1, κ |
| Clonality： | Monoclonal |
| Abbre： | CD194;CCR4 |
| Swissprot： | P51679 | Links: https://www.uniprot.org/uniprot/P51679 |
| Cellular Localization： | Membrane |
| Concentration： | 5 μL/Test |
| Storage： | This product can be stored at 2-8°C for 12 months. Do not freeze. |
| CloneNo： | L291H4 |
| Conjugation： | PerCP/Cyanine 5.5 |
| Background： | CD194, also known as CCR4, is a CC chemokine receptor. It binds CCL17 and CCL22 and is expressed on a subset of T and B cells, basophils, monocytes, and NK cells. Human Th2 cells are characterized by the expression of CCR4 and CCR8, and these receptors are regulated differently during Th2 development. Human peripheral blood Tregs can be divided into two distinct populations based on the expression of CCR4. Freshly isolated Tregs express CCR4 and presumably represent memory-type Tregs, and CCR4- Tregs require CD3-mediated activation to acquire a regulatory activity. Depletion of CCR4+ T cells leads to Th1-type polarization of CD4+ T cells and augmentation of CD8+ T cell responses to tumor antigens. CCR4 and its ligands are important for the recruitment of memory T cells into the skin in various cutaneous immune diseases. |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Form： | Liquid |
| Conjugation Information： | PerCP/Cyanine5.5 is designed to be excited by the blue laser (488 nm) and detected using an optical filter centered near 675 nm (e.g., a 690/50 nm bandpass filter). |
| Spectrum： | |
| Storage Buffer： | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Expiration Date： | 12个月 |
| Shipping： | 冰袋 |
| Host： | Mouse |
| Isotype Control： | PerCP/Cyanine5.5 Mouse IgG1, κ Isotype Control[MOPC-21] | Links: /p-percp_cyanine5_5_mouse_igg1_isotype_control_mopc_21-e_ab_f09792j |
| Alternate Names： | CC-CKR-4, CKR4, CMKBR4, ChemR13, HGCN:14099, K5-5, MGC88293 |
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