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| 产品货号： | E-AB-F1037J |
|---|---|
| 英文名称： | PerCP/Cyanine5.5 Anti-Human CD40 Antibody[3A8] |
| 产品分类： | 流式抗体 |
| 说明书（链接）： | https://789.bio/ea/Wv5aH0 |
| Reactivity： | Human |
| Isotype： | Mouse IgG2a, κ |
| Clonality： | Monoclonal |
| Abbre： | CD40 |
| Swissprot： | P25942 | Links: https://www.uniprot.org/uniprot/P25942 |
| Cellular Localization： | Membrane |
| Concentration： | 5 μL/Test |
| Storage： | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| CloneNo： | 3A8 |
| Conjugation： | PerCP/Cyanine 5.5 |
| Background： | CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis. |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Form： | Liquid |
| Conjugation Information： | PerCP/Cyanine5.5 is designed to be excited by the blue laser (488 nm) and detected using an optical filter centered near 675 nm (e.g., a 690/50 nm bandpass filter). |
| Spectrum： | |
| Storage Buffer： | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Expiration Date： | 12个月 |
| Shipping： | 冰袋 |
| Host： | Mouse |
| Isotype Control： | PerCP/Cyanine5.5 Mouse IgG2a, κ Isotype Control[C1.18.4] | Links: /p-percp_cyanine5_5_mouse_igg2a_isotype_control_c1_18_4-e_ab_f09802j |
| Gene ID： | 958 | Links: https://www.ncbi.nlm.nih.gov/gene/958 |
| Alternate Names： | B-cell surface antigen CD40, Bp50, CD40, CD40L receptor, Cd40, Tnfrsf5, Tumor necrosis factor receptor superfamily member 5 |
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