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| 产品货号： | E-AB-F1021UE |
|---|---|
| 英文名称： | APC Anti-Mouse CD22 Antibody[Cy34.1] |
| 产品分类： | 流式抗体 |
| 说明书（链接）： | https://789.bio/ea/qTWDa5 |
| Reactivity： | Mouse |
| Isotype： | Mouse IgG1, κ |
| Clonality： | Monoclonal |
| Abbre： | CD22 |
| Swissprot： | P35329 | Links: https://www.uniprot.org/uniprot/P35329 |
| Cellular Localization： | Membrane |
| Concentration： | 0.2 mg/mL |
| Storage： | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| CloneNo： | Cy34.1 |
| Conjugation： | APC |
| Background： | The Cy34.1 monoclonal antibody specifically binds to the B-lymphocyte differentiation antigen CD22 on strains having the Lyb-8.2 alloantigen (e.g., A, BALB/c, CBA, C3H/He, C57BL, C57L, C58, SJL, SWR, but not AKR, DBA/1, DBA/2, NZB, PL). CD22 is expressed at high levels on mature peripheral B lymphocytes (follicular and marginal zone), B-1 cells (CD5+ B cells), and plasma cells. It is a member of the Ig gene superfamily and associates with the B-cell antigen receptor. Its sialic acid- binding immunoglobulin-like lectin (siglec) extracellular region mediates B-cell adhesion to ligands on endothelial cells in the bone marrow. Its intracellular domain is phosphorylated after cross-linking of antigen receptor or MHC class II antigen. It is involved in negative regulation of B-cell activation and protection from autoimmunity. B-cell proliferative responses to LPS or anti-mouse Ig µ chain are augmented in the presence of Cy34.1 mAb. |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Form： | Liquid |
| Conjugation Information： | APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). |
| Spectrum： | |
| Storage Buffer： | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Expiration Date： | 12个月 |
| Shipping： | 冰袋 |
| Host： | Mouse |
| Isotype Control： | APC Mouse IgG1, κ Isotype Control[MOPC-21] | Links: /p-apc_mouse_igg1_isotype_control_mopc_21-e_ab_f09793e |
| Gene ID： | 12483 | Links: https://www.ncbi.nlm.nih.gov/gene/12483 |
| Alternate Names： | Siglec2, B-cell receptor CD22, B-lymphocyte cell adhesion molecule, BL-CAM, CD22, Cd22, Lyb-8, Sialic acid-binding Ig-like lectin 2, Siglec-2, T-cell surface antigen Leu-14 |
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