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| 产品货号： | E-AB-F09870 |
|---|---|
| 英文名称： | AF/LE Purified Anti-Mouse CD161/NK1.1 Antibody[PK136] |
| 产品分类： | 流式纯抗 |
| 说明书（链接）： | https://789.bio/ea/VSpqHR |
| Reactivity： | Mouse |
| Isotype： | Mouse IgG2a, κ |
| Clonality： | Monoclonal |
| Abbre： | CD161/NK1.1 |
| Swissprot： | P27814,P27812,Q99JB4 | Links: https://www.uniprot.org/uniprot/P27814, https://www.uniprot.org/uniprot/P27812, https://www.uniprot.org/uniprot/Q99JB4 |
| Concentration： | ≥ 1 mg/mL |
| Storage： | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Research Areas： | Immunology; Innate Immunity |
| CloneNo： | PK136 |
| Conjugation： | None (AF/LE) |
| Background： | NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers. |
| Leadtime： | 咨询 |
| Applications： | FCM;Activ;Block |
| Storage Buffer： | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Expiration Date： | 12个月 |
| Shipping： | Ice bag |
| Host： | Mouse |
| Alternate Names： | CD161 antigen-like family member C, CD161/NK1.1, CD161c, Killer cell lectin-like receptor subfamily B member 1C, Klrb1c, Ly-55c, NKR-P1 40, NKR-P1.9, NKR-P1C |
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