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| 产品货号： | E-AB-F1011A |
|---|---|
| 英文名称： | Purified Anti-Mouse CD62L Antibody[Mel14] |
| 产品分类： | 流式纯抗 |
| 说明书（链接）： | https://789.bio/ea/PVmSlH |
| Reactivity： | Mouse |
| Isotype： | Rat IgG2a, κ |
| Verified Samples： | Verified Samples in FCM: C57/BL6 Mouse splenocytes |
| Dilution： | FCM 2 μg/mL(1×10^5-5×10^5 cells) |
| Clonality： | Monoclonal |
| Abbre： | CD62L |
| Swissprot： | P18337 | Links: https://www.uniprot.org/uniprot/P18337 |
| Concentration： | ≥ 1 mg/mL |
| Storage： | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Research Areas： | Cell Adhesion; Cell Biology; Costimulatory Molecules; Immunology; Innate Immunity |
| CloneNo： | Mel14 |
| Conjugation： | Unconjugated |
| Background： | CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naïve T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte ‘rolling’ on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naïve, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1. |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Storage Buffer： | PBS, pH 7.2. Contains 0.05% proclin 300. |
| Expiration Date： | 12个月 |
| Shipping： | Ice bag |
| Host： | Rat |
| Alternate Names： | CD62L, CD62 antigen-like family member L, L-selectin, LAM-1, LECAM1, Lnhr, Ly-22, Ly22, Lymph node homing receptor, Sell |
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