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| 产品货号： | E-AB-F1028A |
|---|---|
| 英文名称： | Purified Anti-Mouse CD40 Antibody[FGK4.5/FGK45] |
| 产品分类： | 流式纯抗 |
| 说明书（链接）： | https://789.bio/ea/4RtiW9 |
| Reactivity： | Mouse |
| Isotype： | Rat IgG2a, κ |
| Verified Samples： | Verified Samples in FCM: C57/BL6 Mouse splenocytes |
| Dilution： | FCM 2 μg/mL(1×10^5-5×10^5 cells) |
| Clonality： | Monoclonal |
| Immunogen： | Recombinant Mouse CD40 protein |
| Abbre： | CD40 |
| Swissprot： | P27512 | Links: https://www.uniprot.org/uniprot/P27512 |
| Concentration： | ≥ 1 mg/mL |
| Storage： | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Purification Method： | >98%, Protein A/G purified |
| Research Areas： | Cell Biology; Costimulatory Molecules; Immunology; Neuroscience; Neuroscience Cell Markers |
| CloneNo： | FGK4.5/FGK45 |
| Conjugation： | Unconjugated |
| Background： | CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation. |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Storage Buffer： | PBS, pH 7.2. Contains 0.05% proclin 300. |
| Expiration Date： | 12个月 |
| Shipping： | Ice bag |
| Host： | Rat |
| Alternate Names： | B-cell surface antigen CD40, Bp50, CD40, CD40L receptor, Cd40, Tnfrsf5, Tumor necrosis factor receptor superfamily member 5 |
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