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| 产品货号： | E-AB-F1115A |
|---|---|
| 英文名称： | Purified Anti-Mouse CD119 Antibody[GR-20] |
| 产品分类： | 流式纯抗 |
| 说明书（链接）： | https://789.bio/ea/WayP8G |
| Reactivity： | Mouse |
| Isotype： | Rat IgG2a, κ |
| Clonality： | Monoclonal |
| Abbre： | CD119 |
| Swissprot： | P15261 | Links: https://www.uniprot.org/uniprot/P15261 |
| Concentration： | ≥ 1 mg/mL |
| Storage： | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Research Areas： | Immunology |
| CloneNo： | GR-20 |
| Conjugation： | Unconjugated |
| Background： | CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses. |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Storage Buffer： | PBS, pH 7.2. Contains 0.05% proclin 300. |
| Expiration Date： | 12个月 |
| Shipping： | Ice bag |
| Host： | Rat |
| Alternate Names： | CD119, IFN-gamma-R-alpha, IFN-gamma-R1, Ifngr1, Interferon gamma receptor 1 |
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