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| 产品货号： | E-AB-F1051A |
|---|---|
| 英文名称： | Purified Anti-Human CD62L Antibody[DREG56] |
| 产品分类： | 流式纯抗 |
| 说明书（链接）： | https://789.bio/ea/dPdWy1 |
| Reactivity： | Human |
| Isotype： | Mouse IgG1, κ |
| Verified Samples： | Verified Samples in FCM: Human peripheral blood lymphocytes |
| Dilution： | FCM 2 μg/mL(1×10^5-5×10^5 cells) |
| Clonality： | Monoclonal |
| Abbre： | CD62L |
| Swissprot： | P14151 | Links: https://www.uniprot.org/uniprot/P14151 |
| Concentration： | ≥ 1 mg/mL |
| Storage： | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Research Areas： | Cell Adhesion; Cell Biology; Costimulatory Molecules; Immunology; Innate Immunity |
| CloneNo： | DREG56 |
| Conjugation： | Unconjugated |
| Background： | CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer’s patches. It also plays a role in leukocyte rolling on activated endothelial cells. |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Storage Buffer： | PBS, pH 7.2. Contains 0.05% proclin 300. |
| Expiration Date： | 12个月 |
| Shipping： | Ice bag |
| Host： | Mouse |
| Alternate Names： | CD62L, CD62 antigen-like family member L, L-selectin, LAM-1, LECAM1, Lnhr, Ly-22, Ly22, Lymph node homing receptor, Sell |
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