| Background： |
CD5, also known as Leu-1, is a type I transmembrane protein belonging to the scavenger receptor cysteine-rich (SRCR) superfamily. It is expressed on thymocytes, T cells and the B1a subpopulation of B cells. CD5 binds the C-type lectin, CD72, and modulates signaling through the antigen receptors on T and B cells. CD5 has been shown to provide either positive or negative co-stimulatory signals depending on cell type to regulate immune responses. |
| Alternate Names： |
LymphocyteantigenT1/Leu, Lymphocyte antigen T1/Leu, T-cellsurfaceglycoproteinCD, T-cell surface glycoprotein CD, OTTHUMP, LEU, CD5, LEU1, T1, CD 5, CD5 antigen, CD5 antigen (p56 62), CD5 molecule, Leu-1, Ly-1, LyA, LymphocyteantigenT1/Leu-1, OTTHUMP00000236973, T-cellsurfaceglycoproteinCD5, Tp67, T-cell surface glycoprotein CD5, Lymphocyte antigen T1/Leu-1, Tp67, Leu-1, Ly-1, CD 5, CD5, CD5 antigen (p56 62), CD5 antigen, CD5 molecule, CD5, LEU1, LyA, Lymphocyte antigen T1/Leu-1, OTTHUMP00000236973, T-cell surface glycoprotein CD5, T1 |
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