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| 产品货号： | AN002900P |
|---|---|
| 英文名称： | Purified Anti-Human CD180 Antibody[G28-8] |
| 产品分类： | 流式纯抗 |
| 说明书（链接）： | https://789.bio/ea/qP8leL |
| Reactivity： | Human |
| Isotype： | Mouse IgG1, κ |
| Verified Samples： | Verified Samples in FCM: Human peripheral blood lymphocytes |
| Dilution： | FCM 2 μg/mL(1×10^5-5×10^5 cells) |
| Clonality： | Monoclonal |
| Immunogen： | Recombinant Human CD180 protein |
| Abbre： | CD180 |
| Swissprot： | Q99467 | Links: https://www.uniprot.org/uniprot/Q99467 |
| Concentration： | ≥ 1 mg/mL |
| Storage： | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Purification Method： | >98%, Protein A/G purified |
| Research Areas： | Immunology;Microbiology |
| CloneNo： | G28-8 |
| Conjugation： | Unconjugated |
| Background： | CD180, also known as RP105, is a 105 kD member of the toll-like receptor (TLR) family and is expressed on most B cells, monocytes/macrophages and dendritic cells. The TLR family’s structural characteristics are critically involved in protein-protein signaling interactions leading to the activation of the innate immune system. Additionally, MD-1, a secretory protein, associates with CD180 (RP105) at the cell surface and this complex, in conjunction with TLR4, recognizes bacterial LPS. The human CD180 (RP105) gene maps to 5q12. The MHR73-11 antibody is able to activate B cells and to protect against irradiation- or dexamethasone-induced apoptosis. |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Storage Buffer： | PBS, pH 7.2. Contains 0.05% proclin 300. |
| Expiration Date： | 12个月 |
| Shipping： | Ice bag |
| Host： | Mouse |
| Alternate Names： | LY64, RP105, CD180, Ly78 |
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