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| 产品货号： | E-AB-F1018UH |
|---|---|
| 英文名称： | PE/Cyanine7 Anti-Mouse CD54 Antibody[YN1/1.7.4] |
| 产品分类： | 流式抗体 |
| 说明书（链接）： | https://789.bio/ea/HefPmL |
| Reactivity： | Mouse |
| Isotype： | Rat IgG2b, κ |
| Clonality： | Monoclonal |
| Abbre： | CD54 |
| Swissprot： | P13597 | Links: https://www.uniprot.org/uniprot/P13597 |
| Cellular Localization： | Membrane |
| Concentration： | 0.2 mg/mL |
| Storage： | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| CloneNo： | YN1/1.7.4 |
| Conjugation： | PE/Cyanine 7 |
| Background： | CD54 is a 90 kD immunoglobulin superfamily member also known as ICAM-1 and Ly-47. It is expressed on activated endothelial cells, high endothelial venules (HEV), T and B cells, monocytes/ macrophages, granulocytes, and dendritic cells. CD54 is an important intracellular adhesion molecule that participates in T cell-T cell, T cell-B cell, and T cell-target cell interactions via binding of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). CD54 has also been shown to be involved in lymphocyte trafficking, making it an important molecule in many immune reactions and inflammation. CD54 is also a receptor for rhinovirus. The YN1/1.7.4 antibody has been reported to block binding of mouse CD54 to LFA-1 and Mac-1, inhibit cell-cell adhesion, and function in antigen presentation to T cells and leukocyte migration to inflammatory tissues. |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Form： | Liquid |
| Conjugation Information： | PE/Cyanine7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter). |
| Spectrum： | |
| Storage Buffer： | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Expiration Date： | 12个月 |
| Shipping： | 冰袋 |
| Host： | Rat |
| Isotype Control： | PE/Cyanine7 Rat IgG2b, κ Isotype Control[LTF-2] | Links: /p-pe_cyanine7_rat_igg2b_isotype_control_ltf_2-e_ab_f09843h |
| Gene ID： | 15894 | Links: https://www.ncbi.nlm.nih.gov/gene/15894 |
| Alternate Names： | CD54, Icam-1, Icam1, Intercellular adhesion molecule 1, MALA-2, MyD10 |
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