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| 产品货号： | E-AB-F1235UH |
|---|---|
| 英文名称： | PE/Cyanine7 Anti-Mouse CD51 Antibody[RMV-7] |
| 产品分类： | 流式抗体 |
| 说明书（链接）： | https://789.bio/ea/XrL0CG |
| Reactivity： | Mouse |
| Isotype： | Rat IgG1, κ |
| Clonality： | Monoclonal |
| Abbre： | CD51 |
| Swissprot： | P43406 | Links: https://www.uniprot.org/uniprot/P43406 |
| Cellular Localization： | Membrane |
| Concentration： | 0.2 mg/mL |
| Storage： | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| CloneNo： | RMV-7 |
| Conjugation： | PE/Cyanine 7 |
| Background： | CD51 is a 140 kD protein, also known as αV integrin, vitronectin receptor, and integrin αV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins β1, β3, β5 or β6; these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The αvintegrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity. |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Form： | Liquid |
| Conjugation Information： | PE/Cyanine7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter). |
| Spectrum： | |
| Storage Buffer： | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Expiration Date： | 12个月 |
| Shipping： | 冰袋 |
| Host： | Rat |
| Isotype Control： | PE/Cyanine7 Rat IgG1, κ Isotype Control[HRPN] | Links: /p-pe_cyanine7_rat_igg1_isotype_control_hrpn-e_ab_f09823h |
| Gene ID： | 16410 | Links: https://www.ncbi.nlm.nih.gov/gene/16410 |
| Alternate Names： | ITGAV, Integrin alpha-V, Integrin αV chain, Vitronectin Receptor, αV integrin |
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