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| 产品货号： | E-AB-F1131UH |
|---|---|
| 英文名称： | PE/Cyanine7 Anti-Mouse CD279/PD-1 Antibody[29F.1A12] |
| 产品分类： | 流式抗体 |
| 说明书（链接）： | https://789.bio/ea/1ivrbT |
| Reactivity： | Mouse |
| Isotype： | Rat IgG2a, κ |
| Clonality： | Monoclonal |
| Abbre： | CD279;PD-1 |
| Swissprot： | Q02242 | Links: https://www.uniprot.org/uniprot/Q02242 |
| Cellular Localization： | Membrane |
| Concentration： | 0.2 mg/mL |
| Storage： | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| CloneNo： | 29F.1A12 |
| Conjugation： | PE/Cyanine 7 |
| Background： | CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts. |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Form： | Liquid |
| Conjugation Information： | PE/Cyanine7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter). |
| Spectrum： | |
| Storage Buffer： | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Expiration Date： | 12个月 |
| Shipping： | 冰袋 |
| Host： | Rat |
| Isotype Control： | PE/Cyanine7 Rat IgG2a, κ Isotype Control[2A3] | Links: /p-pe_cyanine7_rat_igg2a_isotype_control_2a3-e_ab_f09833h |
| Gene ID： | 18566 | Links: https://www.ncbi.nlm.nih.gov/gene/18566 |
| Alternate Names： | Programmed Death-1, PD-1 |
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