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| 产品货号： | E-AB-F1029UH |
|---|---|
| 英文名称： | PE/Cyanine7 Anti-Mouse CD122/IL-2RB Antibody[5H4] |
| 产品分类： | 流式抗体 |
| 说明书（链接）： | https://789.bio/ea/u1ubL4 |
| Reactivity： | Mouse |
| Isotype： | Rat IgG2a, κ |
| Clonality： | Monoclonal |
| Abbre： | CD122;IL-2RB |
| Swissprot： | P16297 | Links: https://www.uniprot.org/uniprot/P16297 |
| Cellular Localization： | Membrane |
| Concentration： | 0.2 mg/mL |
| Storage： | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| CloneNo： | 5H4 |
| Conjugation： | PE/Cyanine 7 |
| Background： | CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis. |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Form： | Liquid |
| Conjugation Information： | PE/Cyanine7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter). |
| Spectrum： | |
| Storage Buffer： | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Expiration Date： | 12个月 |
| Shipping： | 冰袋 |
| Host： | Rat |
| Isotype Control： | PE/Cyanine7 Rat IgG2a, κ Isotype Control[2A3] | Links: /p-pe_cyanine7_rat_igg2a_isotype_control_2a3-e_ab_f09833h |
| Gene ID： | 16185 | Links: https://www.ncbi.nlm.nih.gov/gene/16185 |
| Alternate Names： | IL-2R subunit beta, CD122, High affinity IL-2 receptor subunit beta, IL-2 receptor subunit beta, IL-2RB, Il2rb, Interleukin-2 receptor subunit beta, p70-75 |
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