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| 产品货号： | E-AB-F1413H |
|---|---|
| 英文名称： | PE/Cyanine7 Anti-Human CD47 Antibody[B6H12] |
| 产品分类： | 流式抗体 |
| 说明书（链接）： | https://789.bio/ea/tHVuqP |
| Reactivity： | Human |
| Isotype： | Mouse IgG1, κ |
| Clonality： | Monoclonal |
| Abbre： | CD47 |
| Swissprot： | Q08722 | Links: https://www.uniprot.org/uniprot/Q08722 |
| Cellular Localization： | Membrane |
| Storage： | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| CloneNo： | B6H12 |
| Conjugation： | PE/Cyanine 7 |
| Background： | CD47 also known as Rh-associated protein, gp42, integrin-associated protein (IAP), and neurophilin, is a 42-52 kD member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. Two splice variants have been described in the cytoplasmic tail, the shorter form is expressed in bone-marrow-derived cells, endothelial cells, and fibroblasts while the longer form is expressed by neural tissues. CD47 expression is widely distributed in hematopoietic cells including thymocytes, T cells, B cells, monocytes, platelets, and erythrocytes as well as epithelial cells, endothelial cells, fibroblasts, and neural tissues. CD47 functions as an adhesion molecule and thrombospondin receptor and is non-covalently associated with β3 integrins CD51/CD61, CD41/CD61. Thrombospondin is a ligand for CD47; in the absence of CD47 mice show defects in host defense and β3 integrin-dependent ligand binding, migration, and cellular activation. CD47 is also part of the Rh complex on erythrocytes. |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Form： | Liquid |
| Conjugation Information： | PE/Cyanine7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter). |
| Spectrum： | |
| Storage Buffer： | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Expiration Date： | 12个月 |
| Shipping： | 冰袋 |
| Host： | Mouse |
| Isotype Control： | PE/Cyanine7 Mouse IgG1, κ Isotype Control[MOPC-21] | Links: /p-pe_cyanine7_mouse_igg1_isotype_control_mopc_21-e_ab_f09792h |
| Gene ID： | 961 | Links: https://www.ncbi.nlm.nih.gov/gene/961 |
| Alternate Names： | IAP, Rh-associated protein, gp42, integrin-associated protein, neurophilin |
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