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| 产品货号： | E-AB-F1381H |
|---|---|
| 英文名称： | PE/Cyanine7 Anti-Human CD158b/j Antibody[DX27] |
| 产品分类： | 流式抗体 |
| 说明书（链接）： | https://789.bio/ea/DVDxDG |
| Reactivity： | Human |
| Isotype： | Mouse IgG2a, κ |
| Clonality： | Monoclonal |
| Abbre： | CD158b/j |
| Swissprot： | P43627,P43628 | Links: https://www.uniprot.org/uniprot/P43627, https://www.uniprot.org/uniprot/P43628 |
| Cellular Localization： | Membrane |
| Concentration： | 5μL/Tests |
| Storage： | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| CloneNo： | DX27 |
| Conjugation： | PE/Cyanine 7 |
| Background： | CD158b is expressed on natural killer cells and a subset of T cells. It is a member of the immunoglobulin superfamily containing two immunoglobulin C2-type domains. Both variants and alternative isoforms of CD158b have been reported. The interaction of CD158b with specific HLA-C antigens on a target cell (HLA-Cw1, HLA-Cw3, HLA-Cw7 alleles, for example) inhibits cytotoxicity and prevents target cell lysis and death. The interactions between KIR and MHC class I are thought to be important in NK cell and T cell regulation following antigen stimulation. The absence of ligands for KIRs may lower the threshold for activation through activating receptors and increase inflammation and susceptibility to autoimmune disease. |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Form： | Liquid |
| Conjugation Information： | PE/Cyanine7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter). |
| Spectrum： | |
| Storage Buffer： | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Expiration Date： | 12个月 |
| Shipping： | 冰袋 |
| Host： | Mouse |
| Isotype Control： | PE/Cyanine7 Mouse IgG2a, κ Isotype Control[C1.18.4] | Links: /p-pe_cyanine7_mouse_igg2a_isotype_control_c1_18_4-e_ab_f09802h |
| Gene ID： | 3803 | Links: https://www.ncbi.nlm.nih.gov/gene/3803 |
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