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| 产品货号： | E-AB-F1351UD |
|---|---|
| 英文名称： | PE Anti-Mouse/Rat Foxp3 Antibody[FJK-16s] |
| 产品分类： | 流式抗体 |
| 文献（数量）： | 4 |
| 说明书（链接）： | https://789.bio/ea/iiPORR |
| Reactivity： | Mouse;Rat |
| Isotype： | Rat IgG2a, κ |
| Clonality： | Monoclonal |
| Abbre： | Foxp3 |
| Swissprot： | Q99JB6 | Links: https://www.uniprot.org/uniprot/Q99JB6 |
| Cellular Localization： | Nucleus;Cytoplasm |
| Concentration： | 0.2 mg/mL |
| Storage： | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| CloneNo： | FJK-16s |
| Conjugation： | PE |
| Background： | FOXP3 is a 47 kD transcription factor, also known as Forkhead box protein P3, Scurfin, JM2, or IPEX. It is proposed to be a master regulatory gene and more specific marker of T regulatory cells than most cell surface markers (such as CD4 and CD25). Transduced expression of FOXP3 in CD4+/CD25– cells has been shown to induce GITR, CD103, and CTLA4 and impart a T regulatory cell phenotype. FOXP3 is mutated in X-linked autoimmunity-allergic dysregulation syndrome (XLAAD or IPEX) in humans and in “scurfy” mice. Overexpression of FOXP3 has been shown to lead to a hypoactive immune state suggesting that this transcriptional factor is a central regulator of T cell activity. |
| Leadtime： | 咨询 |
| Applications： | ICFCM |
| Form： | Liquid |
| Conjugation Information： | PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter). |
| Spectrum： | |
| Storage Buffer： | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Expiration Date： | 12个月 |
| Shipping： | 冰袋 |
| Host： | Rat |
| Isotype Control： | PE Rat IgG2a, κ Isotype Control[2A3] | Links: /p-pe_rat_igg2a_isotype_control_2a3-e_ab_f09833d |
| Gene ID： | 20371 | Links: https://www.ncbi.nlm.nih.gov/gene/20371 |
| Alternate Names： | IPEXJM2ScurfinZinc finger protein JM2, Forkhead box protein P3 |
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