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| 产品货号： | E-AB-F1112UD |
|---|---|
| 英文名称： | PE Anti-Mouse CD45R/B220 Antibody[RA3.3A 1/6.1] |
| 产品分类： | 流式抗体 |
| 说明书（链接）： | https://789.bio/ea/i5Smb9 |
| Reactivity： | Mouse |
| Isotype： | Rat IgM, κ |
| Clonality： | Monoclonal |
| Abbre： | CD45R;B220 |
| Cellular Localization： | Membrane |
| Concentration： | 0.2 mg/mL |
| Storage： | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| CloneNo： | RA3.3A1/6.1 |
| Conjugation： | PE |
| Background： | CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity. |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Form： | Liquid |
| Conjugation Information： | PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter). |
| Spectrum： | |
| Storage Buffer： | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Expiration Date： | 12个月 |
| Shipping： | 冰袋 |
| Host： | Rat |
| Isotype Control： | PE Rat IgM, κ Isotype Control[RTK2118] | Links: /p-pe_rat_igm_isotype_control_rtk2118-e_ab_f09773d |
| Gene ID： | 19264,5788 | Links: https://www.ncbi.nlm.nih.gov/gene/19264,5788 |
| Alternate Names： | B220 |
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