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| 产品货号： | E-AB-F1233UD |
|---|---|
| 英文名称： | PE Anti-Mouse CD105 Antibody[MJ7/18] |
| 产品分类： | 流式抗体 |
| 文献（数量）： | 1 |
| 说明书（链接）： | https://789.bio/ea/HCCynL |
| Reactivity： | Mouse |
| Isotype： | Rat IgG2a, κ |
| Clonality： | Monoclonal |
| Abbre： | CD105 |
| Swissprot： | Q63961 | Links: https://www.uniprot.org/uniprot/Q63961 |
| Cellular Localization： | Membrane |
| Concentration： | 0.2 mg/mL |
| Storage： | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| CloneNo： | MJ7/18 |
| Conjugation： | PE |
| Background： | CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and upregulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF-β1, TGF-β3 and modulates TGF-β signaling by interacting with TGF-β receptors I and/or II. CD105 also binds other growth factors such as actvin A, BMP-2, and BMP-7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging and prognosis, and has therapeutic potential for some solid tumors and other angiogenic diseases. |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Form： | Liquid |
| Conjugation Information： | PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter). |
| Spectrum： | |
| Storage Buffer： | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Expiration Date： | 12个月 |
| Shipping： | 冰袋 |
| Host： | Rat |
| Isotype Control： | PE Rat IgG2a, κ Isotype Control[2A3] | Links: /p-pe_rat_igg2a_isotype_control_2a3-e_ab_f09833d |
| Gene ID： | 13805 | Links: https://www.ncbi.nlm.nih.gov/gene/13805 |
| Alternate Names： | END, Endoglin, Eng |
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