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| 产品货号： | E-AB-F1090D |
|---|---|
| 英文名称： | PE Anti-Mouse CD103 Antibody[M290] |
| 产品分类： | 流式抗体 |
| 说明书（链接）： | https://789.bio/ea/vjXHa1 |
| Reactivity： | Mouse |
| Isotype： | Rat IgG2a, κ |
| Clonality： | Monoclonal |
| Abbre： | CD103 |
| Swissprot： | Q60677 | Links: https://www.uniprot.org/uniprot/Q60677 |
| Cellular Localization： | Membrane |
| Concentration： | 5 μL/Test |
| Storage： | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| CloneNo： | M290 |
| Conjugation： | PE |
| Background： | CD103 is a type I transmembrane glycoprotein known as αE integrin or Integrin αIEL chain. It belongs to the integrin family and is primarily found on intestinal intraepithelial lymphocytes (IEL). CD103 is also expressed on a subpopulation of lamina propria T cells, epithelial dendritic cells, lamina propria-derived dendritic cells, and a small subset of peripheral lymphocytes. T regulatory cells express high level of CD103. The CD103 expression on lymphocytes can be induced upon activation and TGF-β stimulation. In association with integrin β7, CD103 is expressed as αE/β7 heterodimer. Mature CD103 protein can be cleaved into 2 chains, a 150 kD (C-terminal) chain and a 25 kD (N-terminal) chain, which remain linked by disulfide bonds. CD103 binds to E-cadherin and mediates homing of lymphocytes to the intestinal epithelium. |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Form： | Liquid |
| Conjugation Information： | PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter). |
| Spectrum： | |
| Storage Buffer： | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Expiration Date： | 12个月 |
| Shipping： | 冰袋 |
| Host： | Rat |
| Isotype Control： | PE Rat IgG2a, κ Isotype Control[2A3] | Links: /p-pe_rat_igg2a_isotype_control_2a3-e_ab_f09832d |
| Gene ID： | 16407 | Links: https://www.ncbi.nlm.nih.gov/gene/16407 |
| Alternate Names： | CD103, Integrin alpha M290, Integrin alpha-E, Itgae |
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