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| 产品货号： | E-AB-F1133D |
|---|---|
| 英文名称： | PE Anti-Human CD274/PD-L1 Antibody[29E.2A3] |
| 产品分类： | 流式抗体 |
| 文献（数量）： | 2 |
| 说明书（链接）： | https://789.bio/ea/Hmff5G |
| Reactivity： | Human |
| Isotype： | Mouse IgG2b, κ |
| Clonality： | Monoclonal |
| Abbre： | PD-L1 |
| Swissprot： | Q9NZQ7 | Links: https://www.uniprot.org/uniprot/Q9NZQ7 |
| Cellular Localization： | Membrane |
| Concentration： | 5 μL/Test |
| Storage： | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| CloneNo： | 29E.2A3 |
| Conjugation： | PE |
| Background： | CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells. |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Form： | Liquid |
| Conjugation Information： | PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter). |
| Spectrum： | |
| Storage Buffer： | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Expiration Date： | 12个月 |
| Shipping： | 冰袋 |
| Host： | Mouse |
| Isotype Control： | PE Mouse IgG2b, κ Isotype Control[MPC-11] | Links: /p-pe_mouse_igg2b_isotype_control_mpc_11-e_ab_f09812d |
| Gene ID： | 29126 | Links: https://www.ncbi.nlm.nih.gov/gene/29126 |
| Alternate Names： | B7H1PD-L1PDCD1L1PDCD1LG1PDL1, B7 homolog 1, B7-H, B7-H1, Programmed cell death ligand 1 |
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