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| 产品货号： | E-AB-F1229C |
|---|---|
| 英文名称： | FITC Anti-Human CD279/PD-1 Antibody[EH12.2H7] |
| 产品分类： | 流式抗体 |
| 说明书（链接）： | https://789.bio/ea/nP8OW9 |
| Reactivity： | Human |
| Isotype： | Mouse IgG1, κ |
| Clonality： | Monoclonal |
| Abbre： | CD279;PD-1 |
| Swissprot： | Q15116 | Links: https://www.uniprot.org/uniprot/Q15116 |
| Cellular Localization： | Membrane |
| Concentration： | 5 μL/Test |
| Storage： | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| CloneNo： | EH12.2H7 |
| Conjugation： | FITC |
| Background： | Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion. |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Form： | Liquid |
| Conjugation Information： | FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter). |
| Spectrum： | |
| Storage Buffer： | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Expiration Date： | 12个月 |
| Shipping： | 冰袋 |
| Host： | Mouse |
| Isotype Control： | FITC Mouse IgG1, κ Isotype Control[MOPC-21] | Links: /p-fitc_mouse_igg1_isotype_control_mopc_21-e_ab_f09792c |
| Gene ID： | 5133 | Links: https://www.ncbi.nlm.nih.gov/gene/5133 |
| Alternate Names： | PD1, PDCD1, Protein PD-1, hPD-1 |
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