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| 产品货号： | E-AB-F1159C |
|---|---|
| 英文名称： | FITC Anti-Human CD197/CCR7 Antibody[G043H7] |
| 产品分类： | 流式抗体 |
| 说明书（链接）： | https://789.bio/ea/HqXXXP |
| Reactivity： | Human |
| Isotype： | Mouse IgG2a, κ |
| Clonality： | Monoclonal |
| Abbre： | CD197 |
| Swissprot： | P32248 | Links: https://www.uniprot.org/uniprot/P32248 |
| Cellular Localization： | Membrane |
| Concentration： | 5 μL/Test |
| Storage： | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| CloneNo： | G043H7 |
| Conjugation： | FITC |
| Background： | CCR7, also known as CD197, is a chemokine receptor that binds CCL19 and CCL21. CCR7 and its ligands link innate and adaptive immunity by affecting interactions between T cells and dendritic cells and their downstream effect. Naïve T cells enter the lymph node through high endothelial venules, which express CCL21. Dendritic cells and macrophages enter the lymph node through afferent lymphatics. The encounter of T cells and dendritic cells in the T cell zone is CCR7-dependent. In addition, during immunological surveillance, B cells recirculate between B-cell-rich compartments (follicles or B cell zones) in secondary lymphoid organs, surveying for antigen. After antigen binding, B cells move to the boundary of B and T zones to interact with T-helper cells; this B cell migration is directed by CCR7 and its ligands. CCR7-positive cancer cell expression has been associated with lymph node metastasis. |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Form： | Liquid |
| Conjugation Information： | FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter). |
| Spectrum： | |
| Storage Buffer： | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Expiration Date： | 12个月 |
| Shipping： | 冰袋 |
| Host： | Mouse |
| Isotype Control： | FITC Mouse IgG2a, κ Isotype Control[C1.18.4] | Links: /p-fitc_mouse_igg2a_isotype_control_c1_18_4-e_ab_f09802c |
| Gene ID： | 1236 | Links: https://www.ncbi.nlm.nih.gov/gene/1236 |
| Alternate Names： | EBI1EVI1, CCR-7, CDw197, CMKBR7 |
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