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| 产品货号： | E-AB-F1286L |
|---|---|
| 英文名称： | Elab Fluor® 488 Anti-Mouse CD172a/SIRPα Antibody[P84] |
| 产品分类： | 流式抗体 |
| 说明书（链接）： | https://789.bio/ea/peaD80 |
| Reactivity： | Mouse |
| Isotype： | Rat IgG1, κ |
| Clonality： | Monoclonal |
| Abbre： | CD172a;SIRPα |
| Swissprot： | Q64314 | Links: https://www.uniprot.org/uniprot/Q64314 |
| Cellular Localization： | Membrane |
| Storage： | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| CloneNo： | P84 |
| Conjugation： | Elab Fluor®488 |
| Background： | CD172a, also known as SIRPα, is a type I transmembrane protein with one V-set Ig-like and two C-set Ig-like domains in the extracellular portion, and two ITIM motifs and a proline-rich region in the cytoplasmic tail. CD172a is expressed by monocytes, macrophages, myeloid cells, and neuronal tissue. The phosphorylation of SIRPα ITIMs induces the recruitment and activation of the tyrosine phosphatases PTPN6 and PTPN11, resulting in the negative regulation of several biological processes. The ligands of CD172a are CD47, SP-A, and SP-D. |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Form： | Liquid |
| Conjugation Information： | Elab Fluor®488 is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 520 nm (e.g., a 525/40 nm bandpass filter). |
| Spectrum： | |
| Storage Buffer： | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Expiration Date： | 12个月 |
| Shipping： | 冰袋 |
| Host： | Rat |
| Isotype Control： | Elab Fluor®488 Rat IgG1, κ Isotype Control[HRPN] | Links: /p-elab_fluor_488_rat_igg1_isotype_control_hrpn-e_ab_f09822l |
| Gene ID： | 19261 | Links: https://www.ncbi.nlm.nih.gov/gene/19261 |
| Alternate Names： | BIT, CD172 antigen-like family member A, P84, PTPNS1, SHPS-1, SIRPα |
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