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| 产品货号： | AN00324E |
|---|---|
| 英文名称： | APC Anti-Human CD46 Antibody[TRA-2-10] |
| 产品分类： | 流式抗体 |
| 说明书（链接）： | https://789.bio/ea/H0tWeS |
| Reactivity： | Human |
| Isotype： | Mouse IgG1, κ |
| Clonality： | Monoclonal |
| Abbre： | CD46 |
| Swissprot： | P15529 | Links: https://www.uniprot.org/uniprot/P15529 |
| Cellular Localization： | Membrane |
| Concentration： | 5μL/Tests |
| Storage： | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| CloneNo： | TRA-2-10 |
| Conjugation： | APC |
| Background： | CD46 is a transmembrane protein that is known as a complement membrane cofactor protein, MCP, and measles virus receptor. It is widely expressed on leukocytes, platelets, epithelial cells, and fibroblasts. Multiple isoforms of CD46 have been reported with molecular weights ranging from 45-75 kD. CD46 binds complement components C3b and C4b and has been reported to play a role in T cell regulation. In addition to the complement components, CD46 has been shown to interact with moesin, c-Src, tetraspanin 4, c-Yes, and integrin β1. CD46 is also known to be a cellular receptor for human measles virus and human herpes virus-6 as well as other human pathogens, such as Streptococcus pyogenes. Defects in CD46 have been associated with hemolytic-uremic syndrome. |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Form： | Liquid |
| Conjugation Information： | APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). |
| Spectrum： | |
| Storage Buffer： | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Expiration Date： | 12个月 |
| Shipping： | 冰袋 |
| Host： | Mouse |
| Isotype Control： | APC Mouse IgG1, κ Isotype Control[MOPC-21] | Links: /p-apc_mouse_igg1_isotype_control_mopc_21-e_ab_f09792e |
| Gene ID： | 4179 | Links: https://www.ncbi.nlm.nih.gov/gene/4179 |
| Alternate Names： | Complement membrane cofactor protein, measles virus receptor, MCP |
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