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| 产品货号： | E-AB-F1303E |
|---|---|
| 英文名称： | APC Anti-Human CD193/CCR3 Antibody[5E8] |
| 产品分类： | 流式抗体 |
| 说明书（链接）： | https://789.bio/ea/94mPmP |
| Reactivity： | Human |
| Isotype： | Mouse IgG2b, κ |
| Clonality： | Monoclonal |
| Abbre： | CD193;CCR3 |
| Swissprot： | P51677 | Links: https://www.uniprot.org/uniprot/P51677 |
| Cellular Localization： | Membrane |
| Concentration： | 5 μL/Test |
| Storage： | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| CloneNo： | 500000000 |
| Conjugation： | APC |
| Background： | CD193, also known as CC-chemokine receptor 3 (CCR3), CC CKR3, MIP1-alpha receptor like-2, and eotaxin receptor, is a member of the G protein-coupled seven transmembrane receptors family. It binds to the CC chemokines eotaxin, eotaxin-2, and eotaxin-3 with high affinity. CCR3 has also been reported to bind RANTES, MCP-3, and MCP-4 with low affinity. CCR3 receptor is expressed on human eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitor cells, Th2-like lymphocytes, and keratinocytes. CCR3 is thought to play a role in allergic diseases such as bronchial asthma and allergic rhinitis. CCR3 is a co-receptor for HIV-1 and HIV-2, and the binding of eotaxin with CCR3 has been shown to inhibit HIV infection in some cell types. |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Form： | Liquid |
| Conjugation Information： | APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). |
| Spectrum： | |
| Storage Buffer： | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Expiration Date： | 12个月 |
| Shipping： | 冰袋 |
| Host： | Mouse |
| Isotype Control： | APC Mouse IgG2b, κ Isotype Control[MPC-11] | Links: /p-apc_mouse_igg2b_isotype_control_mpc_11-e_ab_f09812e |
| Gene ID： | 1232 | Links: https://www.ncbi.nlm.nih.gov/gene/1232 |
| Alternate Names： | MIP1-alpha receptor like-2eotaxin receptor, C-C chemokine receptor type 3, CC CKR3, CCR |
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