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| 产品货号： | E-AB-FC0008 |
|---|---|
| 英文名称： | Anti-Human CD3-APC/CD4-FITC/CD8a-PE Cocktail |
| 产品分类： | 流式抗体 |
| 文献（数量）： | 1 |
| 说明书（链接）： | https://789.bio/ea/0qHK44 |
| Reactivity： | Human |
| Clonality： | Monoclonal |
| Concentration： | 5 μL/Test |
| Storage： | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| CloneNo： | OKT-3,RPA-T4,OKT-8 |
| Conjugation： | APC;FITC;PE |
| Background： | This product is a FCM antibody cocktail made up of APC Anti-Human CD3 Antibody [Clone: OKT-3] (Mouse IgG2a, κ), FITC Anti-Human CD4 Antibody [Clone: RPA-T4] (Mouse IgG1, κ) and PE Anti-Human CD8a Antibody [Clone: OKT-8] (Mouse IgG2a, κ).;CD3 is a heterotetrameric protein consisting of a CD3γ, a CDδ and 2 CD3ε. It forms complex with TCR. OKT-3 recognize human CD3ε. Human CD3 is expressed on the surface of T cells and NKT cells.;CD4 is also called Leu-3 or T4. It’s a single-chain type I transmembrane glycoprotein, mainly expressed on the surface of T cells, and monocytes/macrophages. In T cells, CD4 forms complex with TCR/CD3 and play important roles in T cell immunity. The target of HIV is CD4+ T cells. Reduction of CD4+ T cells is the main reason of defected immunity after HIV infection.;CD8 is mainly expressed on cytotoxic T cells and also some subpopulations of NK cells. CD8 forms dimer function. In most cells, CD8 is a heterodimer consisting of CD8a and CD8b, but in NK cells nearly all CD8 is homodimer of CD8a. CD8a can form co-receptor with MHC-I restricted TCR to promote T cell antigen recognition and activation. |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Form： | Liquid |
| Conjugation Information： | APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter).FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter). |
| Spectrum： | |
| Storage Buffer： | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Expiration Date： | 12个月 |
| Shipping： | 冰袋 |
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