All products
| 产品货号： | E-AB-F11120 |
|---|---|
| 英文名称： | AF/LE Purified Anti-Mouse CD45R/B220 Antibody[RA3.3A 1/6.1] |
| 产品分类： | 流式纯抗 |
| 说明书（链接）： | https://789.bio/ea/t9l984 |
| Reactivity： | Mouse |
| Isotype： | Rat IgM, κ |
| Clonality： | Monoclonal |
| Abbre： | CD45R/B220 |
| Concentration： | ≥ 1 mg/mL |
| Storage： | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Research Areas： | Cell Biology, Immunology, Inhibitory Molecules, Neuroscience, Neuroscience Cell Markers |
| CloneNo： | RA3.3A1/6.1 |
| Conjugation： | None (AF/LE) |
| Background： | CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity. |
| Leadtime： | 咨询 |
| Applications： | FCM;Cell Sep-Neg |
| Storage Buffer： | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Expiration Date： | 12个月 |
| Shipping： | Ice bag |
| Host： | Rat |
| Alternate Names： | B220 |
评价
清除筛选目前还没有评价