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| 产品货号： | E-AB-F11950 |
|---|---|
| 英文名称： | AF/LE Purified Anti-Human CD28 Antibody[CD28.2] |
| 产品分类： | 流式纯抗 |
| 说明书（链接）： | https://789.bio/ea/ymeHVH |
| Reactivity： | Human |
| Isotype： | Mouse IgG1, κ |
| Verified Samples： | Verified Samples in FCM: Human peripheral blood red |
| Dilution： | FCM 2 μg/mL(1×10^5-5×10^5 cells) |
| Clonality： | Monoclonal |
| Abbre： | CD28 |
| Swissprot： | P10747 | Links: https://www.uniprot.org/uniprot/P10747 |
| Concentration： | ≥ 1 mg/mL |
| Storage： | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Research Areas： | Costimulatory Molecules; Immunology |
| CloneNo： | CD28.2 |
| Conjugation： | None (AF/LE) |
| Background： | CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation. |
| Leadtime： | 咨询 |
| Applications： | FCM;Activ |
| Storage Buffer： | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Expiration Date： | 12个月 |
| Shipping： | Ice bag |
| Host： | Mouse |
| Alternate Names： | GPSAT, GYPA, HGpMiX, MNS, PAS2 |
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