Elab Fluor® 647 Anti-Mouse CD226 Antibody[480.1]
¥672.00 – ¥2,160.00
PE Anti-Human CD74 Antibody[LL1]
¥1,200.00 – ¥4,680.00
Purified Anti-Human CD74 Antibody[LL1]
¥500.00 – ¥1,230.00
| 应用性 |
FCM ,WB |
|---|---|
| 宿主 |
Mouse |
| 亚型 |
Mouse IgG1, κ |
| 反应性 |
Human |
| 规格 |
100μg ,25μg |
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描述
| 产品货号： | E-AB-F14210P |
|---|---|
| 产品分类： | 流式纯抗 |
| 说明书（链接）： | https://789.bio/ea/dmqLd1 |
| Reactivity： | Human |
| Isotype： | Mouse IgG1, κ |
| Verified Samples： | Verified Samples in FCM: Human peripheral blood lymphocytes;Verified Samples in WB: Raji |
| Dilution： | FCM 2 μg/mL(1×10^5-5×10^5 cells);WB 1:200-1:500 |
| Clonality： | Monoclonal |
| Immunogen： | Recombinant Human CD74 protein |
| Abbre： | CD74 |
| Swissprot： | P04233 | Links: https://www.uniprot.org/uniprot/P04233 |
| Concentration： | ≥ 1 mg/mL |
| Storage： | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Purification Method： | >98%, Protein A/G purified |
| Research Areas： | Immunology |
| CloneNo： | LL1 | Links: /search-category=流式抗体&keywords=LL1 |
| Conjugation： | Unconjugated |
| Background： | Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.Class-II-associated invariant chain peptideBinds to the peptide-binding site of MHC class II alpha/beta heterodimers forming an alpha-beta-CLIP complex, thereby preventing the loading of antigenic peptides to the MHC class II complex until its release by HLA-DM in the endosome.1 PublicationIsoform p41Stabilizes the conformation of mature CTSL by binding to its active site and serving as a chaperone to help maintain a pool of mature enzyme in endocytic compartments and extracellular space of antigen-presenting cells (APCs). Has antiviral activity by stymieing the endosomal entry of Ebola virus and coronaviruses, including SARS-CoV-2.Disrupts cathepsin-mediated Ebola virus glycoprotein processing, which prevents viral fusion and entry. This antiviral activity is specific to p41 isoform. |
| Calculated MW： | 34 kDa |
| Observed MW： | 30-35 kDa |
| Leadtime： | 咨询 |
| Applications： | FCM;WB | Links: /resource-products_alerts-detail-147 |
| Storage Buffer： | PBS, pH 7.2. Contains 0.05% proclin 300. |
| Expiration Date： | 12个月 |
| Shipping： | Ice bag |
| Host： | Mouse |
| Alternate Names： | HLA class II histocompatibility antigen gamma chain, HLADG, Ia antigen-associated invariant chain, Ia-GAMMA II, Ii, p33, CD74 HLA-DR antigens-associated invariant chain, DHLAG, CD74, invariant chain, CD 74, CD74 antigen, CD74 antigen (invariant polypeptide of major histocompatibility complex, CD74 molecule, class II antigen-associated), class II invariant chain, CLIP, Gamma chain of class II antigens, HG2A, HLA DR antigens associated invariant chain, HLA DR gamma, HLADR antigens associated invariant chain, HLA-DR antigens-associated invariant chain, HLA-DR-gamma, Ia antigen associated invariant chain, Ia associated invariant chain, Ia gamma, Ia-GAMMA, Invariant polypeptide of major histocompatibility complex class II antigen associated, la-gamma, major histocompatibility complex, Major histocompatibility complex class II invariant chain, MHC HLA DR gamma chain, MHC HLA-DR gamma chain, p35, Protein 41, CD74, DHLAG, HLA class II histocompatibility antigen gamma chain, HLADG, Ia antigen-associated invariant chain, p33, CD 14, CD_antigen=CD14, CD14, CD14 antigen, CD14 molecule, LPS-R, Mo2, Monocyte differentiation antigen CD14, Monocyte differentiation antigen CD14 urinary form, membrane-bound form, Myeloid cell specific leucine rich glycoprotein, Myeloid cell-specific leucine-rich glycoprotein |
其他信息
| 应用性 |
FCM ,WB |
|---|---|
| 克隆性 |
Monoclonal |
| 克隆号 |
LL1 |
| 偶联物 |
Unconjugated |
| 宿主 |
Mouse |
| 亚型 |
Mouse IgG1, κ |
| 反应性 |
Human |
| 规格 |
100μg ,25μg |
| 蛋白靶标 |
CD74 |
| 品牌 |
Elabscience |
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