APC Anti-Human CD74 Antibody[LL1]
¥1,200.00 – ¥4,680.00
AF/LE Purified Anti-Human CD200R1 Antibody[OX-108]
¥190.00 – ¥420.00
PE/Cyanine7 Anti-Human CD74 Antibody[LL1]
¥1,200.00 – ¥4,680.00
| 应用性 |
FCM |
|---|---|
| 宿主 |
Mouse |
| 亚型 |
Mouse IgG1, κ |
| 反应性 |
Human |
| 规格 |
100Tests ,100Tests×2 ,20Tests |
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描述
| 产品货号： | E-AB-F1421H |
|---|---|
| 英文名称： | PE/Cyanine7 Anti-Human CD74 Antibody[LL1] |
| 产品分类： | 流式抗体 |
| 说明书（链接）： | https://789.bio/ea/d1pimL |
| Reactivity： | Human |
| Isotype： | Mouse IgG1, κ |
| Clonality： | Monoclonal |
| Abbre： | CD74 |
| Swissprot： | P04233 | Links: https://www.uniprot.org/uniprot/P04233 |
| Cellular Localization： | Membrane |
| Concentration： | 5μL/Tests |
| Storage： | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| CloneNo： | LL1 |
| Conjugation： | PE/Cyanine 7 |
| Background： | CD74 is a type II transmembrane glycoprotein also known as MHC class II associated invariant chain, invariant chain, Ii, MHC class II chaperone, and MIF receptor. CD74 exists in four isoforms with molecular masses of 33, 35, 41, and 43 kD, depending on genetic splicing. CD74 is primarily expressed on antigen presenting cells, including B cells, monocytes/macrophages, dendritic cells, and Langerhans cells. It is also expressed by activated T cells and activated endothelial and epithelial cells as well as carcinomas of lung, renal, gastric and thymic origin. The primary function of CD74 is intracellular sorting of MHC class II molecules and regulation of exogenous peptide loading onto MHC class II. It is also involved in the modulation of B cell differentiation and positive selection of CD4+ T cells. It has been reported that CD74 binds MIF (macrophage migration inhibitory factor) and signals through CD44 to regulate innate and adaptive immunity. It is also reported that H. pylori infection occurs through urease B binding of CD74 on gastric epithelial cells, inducing gastric epithelial cell apoptosis, NF-κB activation, and IL-8 production. |
| Leadtime： | 咨询 |
| Applications： | FCM |
| Form： | Liquid |
| Conjugation Information： | PE/Cyanine7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter). |
| Spectrum： | |
| Storage Buffer： | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Expiration Date： | 12个月 |
| Shipping： | 冰袋 |
| Host： | Mouse |
| Isotype Control： | PE/Cyanine7 Mouse IgG1, κ Isotype Control[MOPC-21] | Links: /p-pe_cyanine7_mouse_igg1_isotype_control_mopc_21-e_ab_f09792h |
| Gene ID： | 972 | Links: https://www.ncbi.nlm.nih.gov/gene/972 |
其他信息
| 应用性 |
FCM |
|---|---|
| 克隆性 |
Monoclonal |
| 克隆号 |
LL1 |
| 偶联物 |
PE/Cyanine 7 |
| 宿主 |
Mouse |
| 亚型 |
Mouse IgG1, κ |
| 反应性 |
Human |
| 规格 |
100Tests ,100Tests×2 ,20Tests |
| 蛋白靶标 |
CD74 |
| 品牌 |
Elabscience |
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