APC Anti-Rat CD161 Antibody[3.2.3]
¥960.00 – ¥2,400.00
Purified Anti-Mouse/Rat CD29 Antibody[HMβ1-1]
¥180.00 – ¥400.00
AF/LE Purified Anti-Mouse/Rat CD29 Antibody[HMβ1-1]
¥190.00 – ¥420.00
| 应用性 |
FCM |
|---|---|
| 宿主 |
Armenian Hamster |
| 亚型 |
Armenian Hamster IgG |
| 反应性 |
Mouse/Rat |
| 规格 |
100μg ,25μg |
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描述
| 产品货号： | E-AB-F13090 |
|---|---|
| 产品分类： | 流式纯抗 |
| 说明书（链接）： | https://789.bio/ea/CGVD4C |
| Reactivity： | Mouse/Rat |
| Isotype： | Armenian hamster IgG |
| Verified Samples： | Verified Samples in FCM: Rat bone marrow lymphocytes |
| Dilution： | FCM 2 μg/mL(1×10^5-5×10^5 cells) |
| Clonality： | Monoclonal |
| Immunogen： | Recombinant Mouse CD29 protein |
| Abbre： | CD29 |
| Swissprot： | P49134 | Links: https://www.uniprot.org/uniprot/P49134 |
| Concentration： | ≥ 1 mg/mL |
| Storage： | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Purification Method： | >98%, Protein A/G purified |
| CloneNo： | HMβ1-1 | Links: /search-category=流式抗体&keywords=HMβ1-1 |
| Conjugation： | None (AF/LE) |
| Background： | Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-6/beta-1 (ITGA6:ITGB1) is present in oocytes and is involved in sperm-egg fusion. Integrin alpha-4/beta-1 is a receptor for VCAM1 and recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. When associated with alpha-7/beta-1 integrin, regulates cell adhesion and laminin matrix deposition. Involved in promoting endothelial cell motility and angiogenesis. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process and the formation of mineralized bone nodules. May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and RACK1, serves as a platform for SRC activation or inactivation. Plays a mechanistic adhesive role during telophase, required for the successful completion of cytokinesis (By similarity). ITGA4:ITGB1 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling. ITGA4:ITGB1 and ITGA5:ITGB1 bind to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1. ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1. ITGA5:ITGB1 is a receptor for IL1B and binding is essential for IL1B signaling (By similarity). ITGA5:ITGB3 is a receptor for soluble CD40LG and is required for CD40/CD40LG signaling (By similarity). Plays an important role in myoblast differentiation and fusion during skeletal myogenesis (By similarity). ITGA9:ITGB1 may play a crucial role in SVEP1/polydom-mediated myoblast cell adhesion (By similarity). Integrins ITGA9:ITGB1 and ITGA4:ITGB1 repress PRKCA-mediated L-type voltage-gated channel Ca2+ influx and ROCK-mediated calcium sensitivity in vascular smooth muscle cells via their interaction with SVEP1, thereby inhibit vasocontraction (By similarity). |
| Leadtime： | 咨询 |
| Applications： | FCM | Links: /resource-products_alerts-detail-147 |
| Storage Buffer： | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Expiration Date： | 12个月 |
| Shipping： | Order now, ship in 3 days |
| Host： | Armenian hamster |
| Alternate Names： | ITB, ITGB, Itgb1, ITB1 |
其他信息
| 应用性 |
FCM |
|---|---|
| 克隆性 |
Monoclonal |
| 克隆号 |
HMβ1-1 |
| 偶联物 |
None (AF/LE) |
| 宿主 |
Armenian Hamster |
| 亚型 |
Armenian Hamster IgG |
| 反应性 |
Mouse/Rat |
| 规格 |
100μg ,25μg |
| 蛋白靶标 |
CD29 |
| 品牌 |
Elabscience |
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